Disorganized Cartilage and Fibrous Components
Fibrodysplasia
Fibrous dysplasia is a condition characterized by the presence of expanding fibro-osseous tissue in the interior of affected bones. It is characterized by cancellous bone being replaced by fibrous tissue.
Primarily this is a lesion of the growing skeleton.Clinical Characteristics. Fibrous dysplasia may cause pain or limping gait, extremity length discrepancy, bowing, or fractures. This may be associated with endocrine abnormalities such as Albright's syndrome, which consists of the triad of multifocal bone involvement, precocious puberty, and cutaneous pigmentation.
Diagnostics. Radiographic lesions typically are sharply marginated with sclerotic bone and appear as groundglass or lytic expansile lesions of the diaphysis or the metaphysis.
Treatment. Treatment typically includes observation. Surgery may be necessary for those lesions causing progressive deformity, pain, fracture, or impending fracture.