Bed rest
Bed rest is not advised to prevent PTB. A Cochrane database metaanalysis concluded that the practice of prescribing antepartum bed rest to prevent PTB should be discontinued until evidence is produced that it is definitely effective. Strict bed rest in pregnancy include adverse side effects such as muscle atrophy, bone loss, maternal weight loss, increased rates of thromboembolism, psychosocial problems including depression, anxiety, and financial burden. However, there is evidence to show that prolonged standing of longer than 3 hours/day, long work hours, and shift work all increase the risk of PTB (OR 1.16-1.29) (74).
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