Forebrain
Malformations of the forebrain are broad, and range from gross anatomic malformations to microscopic anomalies. Polymicrogyria are increased numbers of small-sized cerebral gyri with shallow disorganized sulci, and this is seen in up to 65% of individuals (72).
Heterotopias are aberrant neural tissues in the form of subependymal nodules. They are present in approximately 40% of cases (34). Microscopic studies have demonstrated disordered cortical lamination, neuronal hypoplasias of the thalamus, and complete or partial agenesis of the olfactory bulbs and tracts. Dysgenesis or agenesis of the corpus callosum may be seen and may also be associated with a malformed cingulated gyrus and septum pellucidum (72). The contribution of these forebrain malformations to the development of cognitive and perceptual dysfunction remains unknown.
More medical literature on Medic.Studio
More on the topic Forebrain:
-
Infectious diseases -
Internal diseases -
Obstetrics and Gynaecology -
Pediatrics -
Veterinary medicine -
-
Conflictology -
Ecology -
Economy -
Finance -
History -
Law -
Medicine -
Philosophy -
Religious studies -