INTRODUCTION
J. PAUL DUFF
Animal Health and Veterinary Laboratories Agency Diseases of Wildlife Scheme (AHVLA DoWS), Great Britain Wildlife Disease Surveillance Partnership, Penrith, Cumbria, UK
Caliciviruses are usually about 40nm in diameter, with cup-shaped surface depressions.
Calix is Latin for ‘cup’ and refers to these depressions, seen in electron microscope preparations. This family of viruses is generally resistant to heat. The isolated virion RNA is infectious, and the viruses replicate in the cytoplasm of host cells. Currently four genera are recognized. The genus Vesivirus includes San Miguel sea lion virus (SMSLV), the vesicular exanthema of swine virus (VESV) and feline calicivirus (FCV), whereas the genus Lagovirus includes rabbit haemorrhagic disease virus (RHDV) and European brown hare syndrome virus (EBHSV). The two remaining genera contain Norwalk-like and Sapporo-like viruses, which are associated with human gastroenteritis. FCV probably infects all species of Felidae.(1)
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