INTRODUCTION
PAUL HEYMAN
Queen Astrid Military Hospital, Epidemiology & Biostatistics Dept, Research Laboratoryfor Vector-Borne Diseases, Brussels, Belgium
The family Bunyaviridae, one of the largest viral families with over 300 viruses, contains five genera: Bunyavirus, Phlebovirus, Nairovirus, Tospovirus and Hantavirus.
The viruses have similar morphological features: the viral particles are spherical or pleomorphic, and range from 80 to 120 nm in size. Most of the 300 members of the Bunya- viridae family are arthropod-borne, the genus Hantavirus being the exception (rodent-borne). Bunyaviruses are single-stranded, enveloped RNA viruses with a genome of negative polarity, divided into three segments. Hantaviruses (genus Hantavirus, prototype virus Hantaan virus (HTNV), named after the Hantaan River in South Korea) are enzootic viruses carried by wild rodents that cause persistent infections in their natural hosts.
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