NOMENCLATURE
The details of mouse nomenclature are beyond the scope of this book, but it is critically important that the full and correct strain, substrain, and mutant allelic or transgene nomenclature be utilized when evaluating pathology and in publications for maximal reproducibility of results.
Being able to “read” the nomenclature of a mouse that is submitted for evaluation is critical for interpreting pathology. Guidelines for mouse nomenclature are available at the International Mouse Nomenclature home page (http://www.informatics.jax.org/ mgihome/nomen/). The Mouse in Biomedical Research: History, Genetics, and Wild Mice (Fox et al. 2007), the mouse chapter in Laboratory Animal Medicine (Fox et al. 2015), and Mouse Genetics (L.M. Silver 1995) are also useful sources of information on mouse genetics, genomics, and nomenclature.
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