Requirement for Mycobactin
Mycobactin is an essential component of media for primary culture of MAP in most circumstances. It is a chelating compound required for iron acquisition and storage, and demonstration of mycobactin dependence is a taxonomic criterion for identification of MAP (Merkal and McCullough, 1982; Thorel et al., 1990). The underlying basis of the requirement for mycobactin and gene regulation of iron metabolism in MAP
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