Stromal cell origin tumors
Mesenchymal tumors
Primary mesenchymal tumors of the liver are rarely observed in both the dog and cat. As a group they tend to behave aggressively and carry a poor prognosis.
Hemangiosarcoma, leiomyosarcoma, fibrosarcoma, osteosarcoma, chondrosarcoma, and liposarcoma have been reported in the dog (Galofaro et al., 2008; Balkman, 2009). Hemangiosarcoma, leiomyosarcoma, rhabdomyosarcoma, and osteosarcoma have been reported in the cat (Balkman, 2009). Cytologically, these tumors tend to share many characteristics, making differentiation based on cytology alone challenging. Close examination of slides can occasionally provide one or two characteristics that raise the index of suspicion for a specific sarcoma. For example, many large spindloid to polygonal cells with small, clear punctate vacuoles and evidence of erythrophagia are suggestive of, but not definitive for, hemangiosarcoma or histiocytic sarcoma (Barger et al., 2012). Elongate spindloid cells associated with extracellular pink fibrillar matrix (collagen) can suggest fibrosarcoma among others. An abundance of large plasmacytoid cells evokes an osteosarcoma, chondrosarcoma, or plasma cell tumor. Strap-cells (large elongate cells with a row of multiple nuclei and faint to prominent cytoplasmic striations) raise suspicion for rhabdomyosarcoma. Even with recognition of one or more of these characteristics, the only accurate cytologic diagnosis is sarcoma, followed by a list of potential differentials.
More medical literature on Medic.Studio
More on the topic Stromal cell origin tumors:
-
Infectious diseases -
Internal diseases -
Obstetrics and Gynaecology -
Pediatrics -
Veterinary medicine -
-
Conflictology -
Ecology -
Economy -
Finance -
History -
Law -
Medicine -
Philosophy -
Religious studies -