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CONCLUSION

Lentiviruses cause severe disease in some host species. The present human pandemic is, unfortu­nately, only the first stage in the evolutionary coadaptation process that is likely to have resulted in the asymptomatic nature of lentiviral infection in Old World nonhuman primates and in some nonprimate lentiviral syndromes as well.

Understanding at the cell biological level how lentiviral infections lead to such different outcomes in different hosts may yield new therapeutic approaches.

ACKNOWLEDGMENT

I thank graduate student Dyana T. Saenz for drawing Figure 1.1.

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Source: Badley A.D. (ed.). Cell Death During HIV Infection. Taylor & Francis,2006. — 511 p.. 2006
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