Contents

Abbreviations xi Contributors xv

SECTION 1

Basics in Obstetrics and Gynaecology

1. Basic science in obstetrics and gynaecology 3

Stergios Doumouchtsis

2. Ethics in obstetrics and gynaecology 33

Frank A.

3. Clinical anatomy of the pelvis and the reproductive organs 44

Thomas Ind

4. Genetics for the obstetrician and gynaecologist 55

Adonis Ioannides

5. Clinical governance 72

Leroy C. Edozien

6. Preconceptional medicine 83

Carmen Binding and Mahantesh Karoshi

7. Obesity in obstetric and gynaecological practice 96

Sukhwinder Sahota and Tahir Mahmood

SECTION 2

Fetomaternal Medicine

8. Maternal physiology 109

Nicola Vousden and Andrew H. Shennan

9. The placenta 120

Eric Jauniaux, Amarnath Bhide, and Graham J. Burton

10. Fetal growth 133

Jane E. Hirst and Aris T. Papageorghiou

11. Prenatal diagnosis 141

Ana Pihas Carrillo and Amarnath Bhide

12. Cardiac disease in pregnancy 151 Philip Steer

13. Diabetes in pregnancy 163

Michael Permezel and Alexis Shub

14. Renal disease in pregnancy 170

David Williams

15. Haematological disorders in pregnancy 186 Amanda Ali and Hassan Shehata

16. Thrombosis and embolism in pregnancy 206 Ian A. Greer

17. General and specific infections in pregnancy including immunization 213

Austin Ugwumadu

18. Psychiatric disorders in pregnancy and the postpartum 233

Arianna Di Florio and Ian Jones

19. Fetal therapy 243

Caitriona Monaghan and Basky Thilaganathan

20. Multiple pregnancy 253

Surabhi Nanda and James P. Neilson

21. Hypertension 268

Laura A. Magee and Peter von Dadelszen

22. Antepartum haemorrhage 284

Gbemisola Okunoye and Justin C. Konje

23. Liver and endocrine diseases in pregnancy 295

Catherine Williamson

24. Neurological disorders in pregnancy 306 Judith N.

25. Respiratory diseases in pregnancy 320

Catherine Nelson-Piercy and Stephen Lapinsky

SECTION 3

Management of Labour

26. The management of labour 331

Devendra Kanagalingam

27. Fetal monitoring during labour 339

Vikram Sinai Talaulikar and Sabaratnam Arulkumaran

28. Obstetric analgesia and anaesthesia 352

Sohail Bampoe and Anthony Addei

29. Obstetric emergencies 358

Kiren Ghag, Cathy Winter, and Tim Draycott

30. Preterm birth 374

Angharad Care and Zarko Alfirevic

31. Prolonged pregnancy 389

Kate F. Walker and Jim G. Thornton

32. Malpresentation, malposition, and cephalopelvic disproportion 395

Deirdre J. Murphy

33. Obstetric procedures 407

Yvonne Kwan Yue Cheng and Tak Yeung Leung

34. Stillbirth 422

David A. Ellwood and Vicki Flenady

35. Postpartum care and problems in the puerperium 435

Stephen J. Robson

36. Induction of labour 447

Andrew Weeks and Julia P. Polk

SECTION 4

Neonatal Care and Neonatal Problems

37. Neonatal care and neonatal problems 461

Vimal Vasu and Neena Modi

39. Ectopic pregnancy 489

Mayank Madhra and Andrew W. Horne

40. The menstrual cycle 500

Lucy HR. Whitaker Karolina Skorupskaite, Jacqueline A. Maybin, and Hilary O.D. Critchley

41. Menstrual disorders, amenorrhea, and dysmenorrhea 511

Ian S. Fraser and Marina Berbic

42. Polycystic ovary syndrome 528

Zhongwei Huang and Eu Leong Yong

43. Pelvic inflammatory disease 536

Gillian Dean and Jonathan Ross

44. Chronic pelvic pain 550 Jacqueline Pui Wah Chung and Tin Chiu Li

45. Endometriosis 560

Arne Vanhie and Thomas DHooghe

46. Menopause 576

Jenifer Sassarini and Mary Ann Lumsden

SECTION 6

Surgical Procedures and Postoperative Care

47. Laparoscopy 587

Stephanie S. Andriputri, Stephen D. Lyons, and Jason A. Abbott

48. Hysteroscopy 597

O.A. O'Donovan and Peter J. O'Donovan

SECTION 7

Benign Disease of the Uterus

49.

Sahana Gupta and Isaac Manyonda

SECTION 5

Gynaecological Problems and Early Pregnancy Loss

SECTION 8

Benign Disease of the Vulva

50. Benign disease of the vulva 627 Rosalind Simpson and David Nunns

38. Miscarriage and recurrent miscarriage 477

Vikram Sinai Talaulikar and Mushi Matjila

SECTION 9

Reproductive Medicine

51. Infertility 639

Smriti Bhatta and Siladitya Bhattacharya

52. Assisted reproduction 655

William Ledger

SECTION 10

Sexual and Reproductive Care

53. Contraception 665

Zephne M. van der Spuy and Petrus S. Steyn

54. Termination of pregnancy 678

Hang Wun Raymond Li and Pak Chung Ho

55. Violence against women and girls 684

Tonye Wokoma and Stephen Lindow

SECTION 11

Urogynaecology and Pelvic Floor Disorders

56. Pelvic organ prolapse 695

Suneetha Rachaneni, Anupreet Dua, and Robert Freeman

57. Urinary incontinence 706

Jay Iyer and Ajay Rane

58. Faecal incontinence and anorectal dysfunction 716

Karen Nugent

59. Childbirth trauma 727

Stergios Doumouchtsis

60. Female sexual dysfunction 743

Ganesh Adaikan

62. Premalignant and malignant disease of the cervix 766

Walter Prendiville

63. Uterine cancer 777

Nomonde H. Mbatani and Dominic G.D. Richards

64. Ovarian, fallopian tube, and peritoneal cancer 787

Jonathan A. Ledermann and Christina Fotopoulou

65. Premalignant and malignant disease of the vulva and vagina 797

Linda Rogers, Maaike Oonk, and Ate van der Zee

66. Gestational trophoblastic disease 809

Hextan YS. Ngan, Karen K.L. Chan, and Siew- Fei Ngu

67. Chemotherapy and biological, targeted, and immune therapies in gynaecological cancers 817 Stephanie Lheureux and Amit M. Oza

68. Radiation therapy in the management of gynaecological cancer 832

Anthony Fyles, Anuja Jhingran, David Gaffney, Dustin Boothe, Marco Carlone, and Tim Craig

69. Palliative care 844

Joanna M. Cain and Shelley M. Kibel

70. Pathology of tumours of the female genital tract 854

Jaime Prat

71. Premalignant disease of the genital tract in pregnancy 867

Andy Nordin and Manas Chakrabarti

72. Cancer in pregnancy 874

Matthys Hendrik Botha

Index 879

SECTION 12

Gynaecological Oncology

61. Cancer screening and prevention

in gynaecology 755

Lynette Denny and Rengaswamy Sankaranarayan