Decision on level of intervention
An open discussion with prospective parents regarding potential outcomes and the likelihood of severe handicap is a vital part of management of extreme threatened PTL. Proactive management including tocolysis to allow transfer to a facility with level 1 neonatal care, the use of antenatal steroids, and prompt neonatal resuscitation will increase the likelihood of survival. Ultrasound estimation of fetal weight may help guide management as mortality rates for infants weighing between 400 and 500 g is 83% (75).
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