REFERENCES

1. Office for National Statistics. Deaths registered in England and Wales: 2014. 2015. Available at: https://www.ons.gov.uk/ peoplepopulationandcommunity/birthsdeathsandmarriages/ deaths/bulletins/deathsregistrationsummarytables/2015-07-15.

2. World Health Organization. Newborns: reducing mortality. 2018. Available at: http://www.who.int/mediacentre/factsheets/fs333/en/.

3. Broekhuijsen K, van Baaren GJ, van Pampus MG, et al. Immediate delivery versus expectant monitoring for hyperten­sive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial. Lancet 2015;385:2492-501.

4. Boyle EM, Johnson S, Manktelow B, et al. Neonatal outcomes and delivery of care for infants born late preterm or moderately pre­term: a prospective population-based study. Arch Dis Child Fetal Neonatal Ed 2015;100:F479-85.

5. March of Dimes, PMNCH, Save the children, WHO. Born Too Soon: The Global Action Report on Preterm Birth (Howson CP, Kinney MV, Lawn JE, eds). Geneva: World Health Organization; 2012.

6. Watson SI, Arulampalam W, Petrou S, et al. The effects of desig­nation and volume of neonatal care on mortality and morbidity outcomes of very preterm infants in England: retrospective popu­lation-based cohort study. BMJ Open 2014;4:e004856.

7. Shlossman PA, Manley JS, Sciscione AC, Colmorgen GH. An ana­lysis of neonatal morbidity and mortality in maternal (in utero) and neonatal transports at 24-34 weeks’ gestation. Am J Perinatol 1997;14:449-56.

8. Costeloe KL, Hennessy EM, Haider S, Stacey F, Marlow N, Draper ES. Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies). BMJ 2012;345:e7976.

9. EXPRESS Group, Fellman V, Hellstrom-Westas L, et al. One-year survival of extremely preterm infants after active perinatal care in Sweden.

10. Larroque B, Breart G, Kaminski M, et al. Survival of very preterm infants: Epipage, a population based cohort study. Arch Dis Child Fetal Neonatal Ed 2004;89:F139-44.

11. Liggins GC, Howie RN. A controlled trial of antepartum gluco­corticoid treatment for prevention of the respiratory distress syn­drome in premature infants. Pediatrics 1972;50:515-25.

12. Roberts D, Dalziel SR. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 2006;3:CD004454.

13. Reynolds AE, Tansey EM (eds). Prenatal corticosteroids for redu­cing morbidity and mortality after preterm birth: the transcript of a witness seminar held by the Wellcome Trust Centre for the history of medicine at UCL, London on 15th June 2004. Available at: https://archive.org/details/prenatalcorticos00tans.

14. Althabe F, Belizan JM, McClure EM, et al. A population­based, multifaceted strategy to implement antenatal cortico­steroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial. Lancet 2015;385:629-39.

15. Wapner RJ, Sorokin Y, Mele L, et al. Long-term outcomes after repeat doses of antenatal corticosteroids. N Engl J Med 2007;357:1190-98

16. National Institute for Health and Care Excellence (NICE). Preterm Labour and Birth. NICE Guideline [NG25]. London: NICE; 2015. Available at: https://www.nice.org.uk/guidance/ng25.

17. Van Baaren GJ, Vis JY, Wilms FF, et al. Predictive value of cer­vical length measurement and fibronectin testing in threatened preterm labor. Obstet Gynecol 2014;123:1185-92.

18. Doyle LW, Crowther CA, Middleton P, Marret S, Rouse D. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus. Cochrane Database Syst Rev 2009;1:CD004661.

19. Chollat C, Enser M, Houivet E, et al. School-age outcomes fol­lowing a randomized controlled trial of magnesium sulfate for neuroprotection of preterm infants.

20. Hadlock FP, Harrist RB, Martinez-Poyer J. In utero analysis of fetal growth: a sonographic weight standard. Radiology 1991;181:129-33.

21. de Onis M, Garza C, Onyango AW, Martorell R (eds). WHO Child Growth Standards. Acta Paediatr Suppl 2006;450:100-101.

22. Papageorghiou AT, Ohuma EO, Altman DG, et al. International standards for fetal growth based on serial ultrasound meas­urements: the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project. Lancet 2014;384:869-79.

23. Hofmeyr GJ, Haws RA, Bergstrom S, et al. Obstetric care in low- resource settings: what, who, and how to overcome challenges to scale up? Int J Gynaecol Obstet 2009;107 Suppl 1:S21-44, S44-45.

24. Stutchfield P, Whitaker R, Russell I, Antenatal Steroids for Term Elective Caesarean Section (ASTECS) Research Team. Antenatal betamethasone and incidence of neonatal respiratory distress after elective caesarean section: pragmatic randomised trial. BMJ 2005;331:662.

25. Prior E, Santhakumaran S, Gale C, Philipps LH, Modi N, Hyde MJ. Breastfeeding after cesarean delivery: a systematic review and meta- analysis of world literature. Am J Clin Nutr 2012;95:1113-35.

26. Hyde MJ, Modi N. The long-term effects of birth by caesarean section: the case for a randomised controlled trial. Early Hum Dev 2012; 88:943-49.

27. Huh SY, Rifas-Shiman SL, Zera CA, et al. Delivery by caesarean section and risk of obesity in preschool age children: a prospective cohort study. Arch Dis Child 2012;97:610-16.

28. Cardwell CR, Stene LC, Joner G, et al. Caesarean section is asso­ciated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies. Diabetologia 2008;51:726-35.

29. Thavagnanam S, Fleming J, Bromley A, et al. A meta-analysis of the association between Caesarean section and childhood asthma. Clin Exp Allergy 2008;38:629-33.

30. Human Embryology and Fertilisation Authority. Treatments. Available at: https://www.hfea.gov.uk/treatments/.

31. Office for National Statistics. Childhood mortality in England and Wales: 2014. Stillbirths, infant and childhood deaths occurring an­nually in England and Wales, and associated risk factors. Available at: http://www.ons.gov.uk/peoplepopulationandcommunity/ birthsdeathsandmarriages/deaths/bulletins/childhoodinfantand perinatalmortalityinenglandandwales/2014.

32. Topp M, Huusom LD, Langhoff-Roos J, et al. Multiple birth and cerebral palsy in Europe: a multicenter study. Acta Obstet Gynecol Scand 2004;83:548-53.

33. Human Embryology and Fertilisation Authority. Decisions to make about your embryos. Available at: http://www.hfea.gov. uk/treatments/explore-all-treatments/decisions-to-make-about- your-embryos/.

34. Office for National Statistics. Childhood, infant and peri­

natal mortality in England and Wales 2013. 2015. Available at: http://www.ons.gov.uk/peoplepopulationandcommunity/

birthsdeathsandmarriages/deaths/bulletins/childhoodinfantand- perinatalmortalityinenglandandwales/2015-03-10 (accessed 24 June 2016).

35. Liu L, Oza S, Hogan D, et al. Global, regional, and national causes of child mortality in 2000-13, with projections to in­form post-2015 priorities: an updated systematic analysis. Lancet 2015;385:430-40.

36. Springett A, Budd J, Draper ES, et al. Congenital Anomaly Statistics 2012: England and Wales. London: British Isles Network of Congenital Anomaly Registers; 2014.

37. Kurinczuk JJ, Hollowell J, Boyd PA, Oakley L, Brocklehurst P, Gray R. The Inequalities in Infant Mortality Project Briefing Paper 4: The Contribution of Congenital Anomalies to Infant Mortality. Oxford: National Perinatal Epidemiology Unit, University of Oxford; 2010.

38. NHS England. New congenital heart disease review. 2014. Available at: https://www.england.nhs.uk/wp-content/uploads/ 2014/09/chd-5-230914.pdf (accessed 15 July 2016).

39. Wren C, Richmond S, Donaldson L. Presentation of congenital heart disease in infancy: implications for routine examination.

40. Thangaratinam S, Brown K, Zamora J, Khan KS, Ewer AK. Pulse oximetry screening for critical congenital heart defects in asymp­tomatic newborn babies: a systematic review and meta-analysis. Lancet 2012;379:2459-64.

41. McDonald SJ, Middleton P, Dowswell T, Morris PS. Effect oftiming of umbilical cord clamping of term infants on maternal and neo­natal outcomes. Cochrane Database Syst Rev 2013;7:CD004074.

42. Rabe H, Diaz-Rossello JL, Duley L, Dowswell T. Effect of timing of umbilical cord clamping and other strategies to influence pla­cental transfusion at preterm birth on maternal and infant out­comes. Cochrane Database Syst Rev 2012;8:CD003248.

43. Raju TN. Timing of umbilical cord clamping after birth for opti­mizing placental transfusion. Curr Opin Paediatr 2013:180-87.

44. Andersson O, Lindquist B, Lindgren M, Stjernqvist K, Domellof M, Hellstrom-Westas L. Effect of delayed cord clamping on neurodevelopment at 4 years of age. JAMA Pediatrics 2015;169:631-38.

45. Allegranzi B, Bagheri Nejad S, Combescure C, et al. Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet 2011;377:228-41.

46. Qazi SA, Stoll BJ. Neonatal sepsis: a major global public health challenge. Pediatr Infect Dis J 2009;28 Suppl 1:S1-2.

47. National Institute for Health and Care Excellence (NICE). Neonatal Infection (Early Onset): Antibiotics for Prevention and Treatment. Clinical guideline [CG149]. London: NICE; 2012. Available at: https://www.nice.org.uk/guidance/CG14.

48. World Health Organization (WHO). WHO Guidelines on Hand Hygiene in Health Care. Geneva: WHO; 2009. Available at: http://apps. who.int/iris/bitstream/10665/44102/1/9789241597906_eng.pdf.

49. CapurroH. Topical Umbilical Cord Care at Birth: RHL Commentary. The WHO Reproductive Health Library. Geneva: World Health Organization; 2004.

50. Karumbi J, Mulaku M, Aluvaala J, English M, Opiyo N.

51. Goldenberg RL, McClure EM, Saleem S. A review of studies with chlorhexidine applied directly to the umbilical cord. Am J Perinatol 2013;30:699-701.

52. Resuscitation Council UK. Resuscitation guidelines. 2015. Available at: https://www.resus.org.uk/resuscitation-guidelines/.

53. Saugstad OD, Ramji S, Soll RF, et al. Resuscitation of newborn in­fants with 21% or 100% oxygen: an updated systematic review and meta-analysis. Neonatology 2008;94:176-82.

54. Tybulewicz AT, Clegg SK, Fonfe GJ, Stenson BJ. Preterm meco­nium staining of the amniotic fluid: associated findings and risk of adverse clinical outcome. Arch Dis Child Fetal Neonatal Ed 2004;89:F328-30.

55. Vain NE, Szyld EG, Prudent LM, Wiswell TE, Aguilar AM, Vivas NI. Oropharyngeal and nasopharyngeal suctioning of meconium- stained neonates before delivery of their shoulders: multicentre, randomised controlled trial. Lancet 2004;364:597-602

56. Wiswell TE, Gannon CM, Jacob J, et al. Delivery room manage­ment of the apparently vigorous meconium-stained neonate: re­sults of the multicenter, international collaborative trial. Pediatrics 2000;105:1-7.

57. Soll RF. Heat loss prevention in neonates. J Perinatol 2008;28 Suppl 1:S57-59.

58. World Health Organization (WHO), Department of Reproductive Health and Research. Thermal Protection of the Newborn: A Practical Guide. Geneva: WHO; 1997.

59. Kent AL, Williams J. Increasing ambient operating theatre temperature and wrapping in polyethylene improves admis­sion temperature in premature infants. J Paediatr Child Health 2008;44:325-31.

60. Moore ER, Anderson GC, Bergman N, Dowswell T. Early skin- to-skin contact for mothers and their healthy newborn infants. Cochrane Database Syst Rev 2012;5:CD003519.

61. Leadford AE, Warren JB, Manasyan A, et al. Plastic bags for pre­vention of hypothermia in preterm and low birth weight infants. Pediatrics 2013;132:e128-34.

62. Oatley HK, Blencowe H, Lawn JE. The effect of coverings, in­cluding plastic bags and wraps, on mortality and morbidity in pre­term and full-term neonates. J Perinatol 2016;36 Suppl 1:S83-89.

63. Horta BL, Victora CG. Long-Term Efijects of Breast Feeding: A Systematic Review. Geneva: World Health Organization; 2013.

64. Roze JC, Darmaun D, Boquien CY, et al. The apparent breast­feeding paradox in very preterm infants: relationship between breast feeding, early weight gain and neurodevelopment based on results from two cohorts, EPIPAGE and LIFT. BMJ Open 2012;2:e000834.

65. Boyd C, Quigley M, Brocklehurst P. Donor breast milk versus in­fant formula for preterm infants: systematic review and meta-ana- lysis. Arch Dis Chld Fetal Neonatal Ed 2006;92:F169-75.

66. National Institute for Health and Care Excellence (NICE). Neonatal Jaundice. Clinical guideline [CG98], updated 2016. London: NICE; 2010. Available at: https://www.nice.org.uk/guid- ance/cg98.

67. American Academy of Pediatrics, Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks ofgestation [published correction appears in Pediatrics 2004;114:1138]. Pediatrics 2004;114:297-316.

68. National Institute for Health and Care Excellence (NICE). Factors that influence hyperbilirubinaemia and kernicterus. In: Neonatal Jaundice. Clinical guideline [CG98], updated 2016. Available at: http://www.ncbi.nlm.nih.gov/books/NBK65114/.

69. British Society of Paediatric Gastroenterology and Nutrition. Guidelines. Available at: https://bspghan.org.uk/guidelines.

70. Kelly DA, Davenport M. Current management of biliary atresia. Arch Dis Child 2007;92:1132-35.

71. Nio M, Ohi R, Miyano T, et al. Five- and 10-year survival rates after surgery for biliary atresia: a report from the Japanese Biliary Atresia Registry. J Pediatr Surg 2003;38:997-1000.

72. The Review on Antimicrobial Resistance. Final report. Available at: http://amr-review.org/Publications (accessed 15 July 2016).

73. Wright KJ, Smith-Collins A, Davis J. G414(P) C-reactive protein without sepsis after birth: development of infant CRP nomo­grams. Arch Dis Child 2016;101:A243.

74. Srinivasan L, Harris MC, Shah SS. Lumbar puncture in the neo­nate: challenges in decision making and interpretation. Semin Perinatol 2012;36:445-53.

75. UNICEF. Breastfeeding assessment tools. Available at: http:// www.unicef.org.uk/BabyFriendly/Resources/Guidance-for- Health-Professionals/Forms-and-checklists/Breastfeeding-as- sessment-form/.

76. McElhinney DB, Hedrick HL, Bush DM, et al. Necrotizing entero­colitis in neonates with congenital heart disease: risk factors and outcomes. Pediatrics 2000;106:1080-87.

77. American College of Obstetricians and Gynecologists. Executive summary: neonatal encephalopathy and neurologic outcome. Obstet Gynecol 2014;123:896-901.

78. Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol 1976;33:696-705.

79. Azzopardi DV, Strohm B, Edwards AD, et al. Moderate hypo­thermia to treat perinatal asphyxial encephalopathy. N Engl J Med 2009;361:1349-58.

80. Azzopardi D, Strohm B, Marlow N, et al. Effects of hypothermia for perinatal asphyxia on childhood outcomes. N Engl J Med 2014;371:140-49.

81. Pauliah SS, Shankaran S, Wade A, Cady EB, Thayyil S. Therapeutic hypothermia for neonatal encephalopathy in low- and middle-in­come countries: a systematic review and meta-analysis. PLoS One 2013;8:e58834.

82. Royal College of Paediatrics and Child Health, National Neonatal Audit Programme. Available at: http://www.rcpch.ac.uk/nnap.

83. Spencer A, Modi N. National neonatal data to support specialist care and improve infant outcomes. Arch Dis Child Fetal Neonatal Ed 2013;98:F175-80.

84. Gale C, Hyde M, Modi N, WHEAT trial development group. Research ethics committee decision-making in relation to an effi­cient neonatal trial. Arch Dis Child 2017;102:F291-98.