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Special contraceptive needs

Postabortion and postpartum contraception

The provision and easy access of postpartum contraception is not only beneficial for the health of the mothers but also for their chil­dren.

Adequate spacing between pregnancies prevents a higher risk of prematurity, low birth weight, fetal death, and early neonatal death (61). Maternal health also benefits through lowering of the risk of uterine rupture and uteroplacental bleeding (62). There is still a high unmet need for modern postpartum contraception (63).

Breastfeeding, modern contraceptive methods, sterilization, and emergency contraception should be considered in all cases. The WHO MEC depicts concerns about the theoretical hormonal effects of combined hormonal contraceptives on the suppression of quality and quantity of milk production as well as possible absorption by the infant. There is also an increased risk of thromboembolism post­partum when using COCs or oestrogen-containing contraceptive methods. It is recommended that the earliest date to start is 21 days postpartum if other risk factors for the development of VTE are ex­cluded (63). In 2015, the WHO updated the recommendations which are now more restrictive for oestrogen-containing contraceptives and less restrictive for progestogen-containing methods (Table 53.5)

According to the United Kingdome National Institute for Health and Care Excellence (NICE) guidelines, methods and timing when to start contraception should be discussed within the first week of the birth, and include the provision of contact details for contracep­tive advice (64, 65).

The IUD is a LARC method with expulsion rates of 5-15 per 100 woman-years of use when used as a postplacental method immedi­ately after caesarean section. The IUD does not affect breastfeeding and is easy to insert in these women, but appears to be associated with a higher perforation rate (>1 per 100) (66).

Contraception provision after abortion should be discussed with women at the initial assessment and documented. Women should be advised of the greater effectiveness of LARC methods. An IUD is a safe, good method to use after both first- and second-trimester surgical abortions. Sterilization can be safely performed at the time of induced abortion although it may be more likely than interval sterilization to be associated with regret (67).

Table 53.5 Latest recommendations from the WHO MEC fifth edition for hormonal contraception postpartum

Recommendations for combined hormonal contraception (CHC) use among breastfeeding women
53.6 and 53.7. The guidance is currently being reviewed and will be on the WHO website available in late 2019.

The adolescent requiring contraception

Adolescence, defined as 10-19 years of age, is a time of physical, sexual, and emotional development and experiences. Adolescents may face pressure to participate in high-risk behaviour, including sexual activity, and have the right to request and receive unbiased contraceptive counselling. They have the right of choice concerning which contraceptive they wish to use. It should be noted that the pre­scriber should know the legal guidelines of the particular statutory body or bodies where they practise (70).

Most contraceptive methods may be offered to adolescents ex­cept permanent methods which are seldom appropriate because of their irreversibility. The adolescent should be advised about the use of a LARC method whenever possible but her choice

Table 53.6 WHO recommendations for use of hormonal contraception for women at high risk of HIV infection and women living with HIV (11,68)

Women at high risk of HIV infection Women at high risk of acquiring HIV can use the following hormonal contraceptive methods (Category 1)

without restriction: COCs, combined injectable contraceptives (CICs), combined contraceptive patches and rings, POPs, and LNG and ETG implants

Women at high risk of acquiring HIV can generally use POIs (DMPA and NET-EN) and LNG-IUDs (Category 2)

Women living with asymptomatic or mild HIV clinical disease (WHO stage 1 or 2) Women living with asymptomatic or mild HIV clinical disease (WHO stage 1 or 2) can use (Category 1)

the following hormonal contraceptive methods without restriction: COCs, CICs, combined contraceptive patches and rings, POPs, POIs (DMPA and NET-EN), and LNG and ETG implants

Women living with asymptomatic or mild HIV clinical disease (WHO stage 1 or 2) can generally use (Category 2) the LNG-IUD

Women living with severe or advanced HIV clinical disease (WHO stage 3 or 4) Women living with severe or advanced HIV clinical disease (WHO stage 3 or 4) can use (Category 1)

the following hormonal contraceptive methods without restriction: COCs, CICs, combined contraceptive patches and rings, POPs, POIs (DMPA and NET-EN), and LNG and ETG implants

Women living with severe or advanced HIV clinical disease (WHO stage 3 or 4) generally should (Category 3)

not initiate use of the LNG-IUD until their illness has improved to asymptomatic or mild HIV (Category 2)

clinical disease (WHO stage 1 or 2)

Women who already have an LNG-IUD inserted and who develop severe or advanced HIV clinical(Category 2 for disease need not have their IUD removed continuation)

CIC, combined injectable contraceptives; COC, combined oral contraceptive pills; DPMA, depot medroxyprogesterone acetate; ETG, etonogestrel; LNG, levonorgestrel; LNG-IUD, levonorgestrel-releasing intrauterine device; NET-EN, norethisterone enanthate; POI, progestogen-only injectable; POP progestogen-only pill.

Source data from World Health Organization. Hormonal contraceptive eligibility for women at high risk of HIV Guidance - Recommendations concerning the use of hormonal contraceptive methods by women at high risk of HIV (2017). https://www.who.int/reproductivehealth/publications/family_planning/HC-and-HIV-2017/en/.

of a contraceptive option will determine what method she is given (71, 72).

Sufficient time for consultation should be provided and these cli­ents must be encouraged to return at any time if they experience problems with their contraceptive choice. Young women have been found to be less tolerant of side effects and abandoning contracep­tion will place them at risk of unintended pregnancy. Correct and consistent condom use must be promoted to prevent STIs and dual protection with another effective method of contraception to pre­vent pregnancy must be encouraged. Adolescents may have specific health concerns or risks which need to be addressed at the first con­sultation. They should have easy access to emergency contraception.

Sexually active young people are more likely to have short-term sexual relationships with more partners and may have a greater risk of STIs, including HIV acquisition. In the counselling and other medical advice concerning infection prevention, all victims of non- consensual coitus should be offered postcoital contraception as well as postexposure prophylaxis for HIV acquisition.

Table 53.7 Women living with HIV using antiretroviral therapy (11)

Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) Women taking any NRTI can use all hormonal contraceptive methods without restriction: COCs, CICs, combined contraceptive patches and rings, POPs, POIs (DMPA and NET-EN), and LNG and ETG implants (Category 1)
Women taking any NRTI can generally use the LNG-IUD, provided that their HIV clinical disease is asymptomatic or mild (WHO Stage 1 or 2) (MEC Category 2)
Women living with severe or advanced HIV clinical disease (WHO stage 3 or 4) and taking any NRTI generally should not initiate use of the LNG-IUD until their illness has improved to asymptomatic or mild HIV clinical disease (MEC Category 3 for initiation)
Women taking any NRTI who already have had an LNG-IUD inserted and who develop severe or advanced HIV clinical disease need not have their IUD removed (MEC Category 2 for continuation)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) Women using NNRTIs containing either efavirenz or nevirapine can generally use COCs, CICs, combined contraceptive patches and rings, POPs, NET-EN, and LNG and ETG implants (MEC Category 2)
Women using efavirenz or nevirapine can use DMPA without restriction (MEC Category 1)
Women taking any NNRTI can generally use the LNG-IUD, provided that their HIV clinical disease is asymptomatic or mild (WHO Stage 1 or 2) (MEC Category 2)
Women living with severe or advanced HIV clinical disease (WHO stage 3 or 4) and taking any NNRTI generally should not initiate use of the LNG-IUD until their illness has improved to asymptomatic or mild HIV clinical disease (MEC Category 3 for initiation)
Women taking any NNRTI who already have had an LNG-IUD inserted and who develop severe or advanced HIV clinical disease need not have their IUD removed (MEC Category 2 for continuation)
NNRTIs containing etravirine and rilpivirine Women using the newer NNRTIs containing etravirine and rilpivirine can use all hormonal contraceptive methods without restriction (MEC Category 1)

CIC, combined injectable contraceptives; COC, combined oral contraceptive pills; DPMA, depot medroxyprogesterone acetate; ETG, etonogestrel; LNG, levonorgestrel; LNG-IUD, levonorgestrel-releasing intrauterine device; NET-EN, norethisterone enanthate; POI, progestogen-only injectable; POP, progestogen-only pill.

Source data from World Health Organization.

Medical Eligibility Criteria for Contraceptive Use: A WHO Family Planning Cornerstone (2015). World Health Organization, 5th edition. http://apps.who.int/iris/bitstream/10665/181468/1/9789241549158_eng.pdf?ua=1 (accessed 26 May 2016).

Contraception at the end of reproductive life

The contraceptive needs of the perimenopausal woman often do not receive adequate attention. These women are still vulnerable in terms of unintentional conception, are usually still sexually active, and pos­sibly may have a new partner which put them at risk of STIs. Ideally, the contraception they are offered should provide them with health benefits as well as contraceptive protection. A pregnancy which oc­curs at the end of reproductive life is often unintended and can cause considerable distress and concern. Many women find the choice of termination of pregnancy unacceptable although at the same time they have not planned a pregnancy in their 40s and 50s (45, 73, 74).

When reviewing the contraceptive options for older women, age alone is not a contraindication for most of the contraceptive methods. The current advice, however, is that the combined contraceptive pill and the injectable progestogen options should be stopped at 50 years of age unless there have been earlier contraindications. Factors such as body mass index, medical problems, and risk factors for cardio­vascular and hypertensive disease will impact contraceptive options (75). The use of hormonal contraception is also protective in terms of certain cancers (76-78).

The COC can usually be utilized after the age of 50 years in a woman with no additional risk factors and consideration should be given to utilize lower-dose pills (79). Unfortunately these are not universally available and are not supplied in many public health sys­tems in developing countries. Similarly, the other delivery methods such as transdermal patches are not available in low-resource settings (80).

The advantages of the combined contraceptive pill are that this impacts positively on bone metabolism and reduces ovarian and endometrial cancer.

Unfortunately there are also considerable risks for thromboembolic disease and arterial disease and there is on­going concern that combined therapy may impact breast cancer and cervical cancer (81).

Progestogen-only contraception has many routes of administra­tion including oral, subdermal, and intramuscular. Many women have unscheduled bleeding which causes concern and the implica­tions of this therapy need to be carefully discussed with potential users (73, 82).

The copper intrauterine contraceptive device has no systemic impact and in addition has the advantage of offering long-term contraception for the perimenopausal woman. Unfortunately many consumers chose not to use this method, despite the very acceptable efficacy record.

Barrier contraception in the older women may be important as often they are involved in new relationships and protection against human papillomavirus and HIV is needed. Condom difficulty has been reported with older partners who may have erectile dysfunc­tion and the use of the female condom has received variable accept­ance. In many countries the diaphragm and the cervical cap are not available and there is considerable concern about the use of spermi­cides which may increase HIV transmission. Natural contraception is always problematic and while sterilization is appropriate in the older woman, she may find this unacceptable.

Advice on when to stop contraception is important in this age group. At present, it is generally accepted that 1 year after the last menstrual bleed if a woman is 50 years or older is a reasonable time to discontinue contraception. In the younger woman, it is recom­mended she should continue contraceptive measures for at least 2 years. When a woman reaches 55 years regardless of her men­strual pattern, it is suggested that no contraceptive method needs to be utilized. There may, however, be indications for further inves­tigations of ongoing bleeding. It must be stressed that hormone re­placement therapy is not a contraceptive option for older women and the healthcare professional should be aware of the patient's particular needs.

Contraception in women with medical disorders

In the past, medical conditions were often regarded as a contra­indication to both contraception and pregnancy. As treatment has improved and management of many medical disorders has been optimized, women who previously would not have considered pregnancy are now requesting contraception and pregnancy man­agement. This involves interdisciplinary consultation and an under­standing of the impact of pregnancy on the underlying condition and of the condition on pregnancy.

Pregnancy may trigger cardiovascular disease or escalate under­lying problems such as autoimmune disorders (83, 84). It is essential that all healthcare providers are aware of the needs of the woman with medical disorders. In some situations pregnancy is totally contraindicated and the client and her partner need to be appro­priately counselled. In many instances, improved medical care will result in stabilization of the patient and the possibility of pregnancy may be considered. It is essential that no pregnancy is unintended, that women are offered appropriate contraception until they de­sire pregnancy and that this contraceptive advice embraces the particular problems of their condition. In women with significant medical conditions it is essential that postpartum contraception is discussed and adequately implemented (85, 86).

The WHO MEC for contraceptive use offer a valuable resource to healthcare providers who are dealing with patients with med­ical problems. It is important that we recognize when pregnancy should be best postponed to optimize the medical condition, and when pregnancy is contraindicated as it will impact the mother's survival. Once women with medical disorders have completed their family, permanent or long-acting contraception should be considered (11).

Maternal death through an unintended pregnancy is a tragedy. It impacts not only the mother and her partner but also all the sur­viving children and results in higher infant and child mortality rates. Ensuring adequate and safe contraceptive provision to women with major medical disorders and ongoing medical input is a cornerstone of good reproductive healthcare.

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