ACUTE TUBULAR NECROSIS

Acute tubular necrosis (without arterial or glomerular lesions) is a common cause of intrinsic renal failure following—(a) sudden hypovolemia/shock, (b) nephrotoxic drug/chemical exposure or (c) infections. These patients usually present with a prolonged diuretic phase after initial oliguria, which can cause severe fluid and electrolyte disturbances.

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