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GENERAL CONSIDERATIONS

Anatomical development of eye is near complete at birth, with its size being ~65% of adult size. However, some development immaturities are common even in term newborns and young infants (Table 26.1) and should be considered during interpretation of ophthalmic findings in this age-group.

In addition, transient corneal haze, hyaloid vascular remnants on posterior lens capsule or optic disc, and retinal hemorrhages are common in preterms, which disappear with maturity.

While periodic ophthalmic screening is indicated in all children for early diagnosis of: (a) developmental or acquired ocular abnormalities, (b) visual/refractory errors, and (c) disorders of ocular motility, e.g. strabismus; all of whom may hamper development of binocular vision with potential risk of amblyopia in

TABLE 26.1: Developmental ophthalmic immaturities at birth

Anatomical

• Thin, translucent, bluish sclera

• Relatively large cornea

• Shallow anterior chamber

• Lightly pigmented iris

• More spherical lens, with Mitternorf dots*

• Pale retina with peppery/mottled pigmentation

• Relatively pale optic disc

• Immature macula (weak foveal light reflex)

Physiological

• Physiological photophobia

• Low visual acuity (~ 6/120 at birth)

• Physiological hypermetropia till 6-7 years

• Physiological strabismus till 3-6 months

• remnants of fetal hyaloid system

TABLE 26.2: Specific indications for ophthalmic assessment

High-risk cases

• Prematurity

• Perinatal complications/ prolonged NICU stay

• Systemic diseases: Diabetes, hypertension, JIA

• Prolonged steroid therapy

• Family history of ophthalmic disease

Clinical indicators

• Delayed visual milestones

• Craniofacial dysmorphism

• Chromosomal/genetic disorders

• Ocular abnormalities: Cataract, glaucoma, retinopathies

• Abnormal eye movements: Nystagmus, strabismus

Poor school performance

developing eye. However, Table 26.2 enumerates high- risk cases, who need comprehensive and more frequent ophthalmic assessment by experts.

26.2

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Source: Agrawal M.. Textbook of Pediatrics. 3rd ed. — CBS Publishers,2025. — 973 p.. 2025
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