Congenital/Hereditary Hydrocephalus
Spontaneous cases of hydrocephalus have been identified in Syrian hamsters housed in a research facility in Switzerland. No obvious behavioral changes were detected in affected animals.
There was no evidence of impairment of reproductive activity in affected animals, and viable offspring were produced. Examination of brains of hydrocephalic hamsters revealed various gradations of involvement, ranging from marked dilation of the lateral ventricles to barely perceptible hydrocephalus detectable only on microscopic examination. Doming of calvaria was absent, and the limitation of the dilation to the lateral ventricles was consistent with stenosis of the cerebral aqueduct. Additional studies failed to identify any infectious or toxic agent that could be the underlying cause. The entity appears to be widespread in hamster stocks in central Europe.
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