Conclusion

Based on the available baseline data, we can confirm that BTB is present in Rwanda. Unfortunately, it remains a neglected disease despite its known socio-economic and public health impact.

Effective control of animal movement in the country can also be used as a way of successfully managing the disease by limiting its further spread into uninfected areas. The effective implementation of the One Health concept would also enhance attempts to effectively prevent, control, and even eradicate the disease in the long term.

Acknowledgment The authors express their appreciation to Mr. Ali Ahsan Bajwa of The Uni­versity of Queensland (UQ), and Dr. Jared Omolo of the United States Centers for Disease Control and Prevention (CDC), Rwanda, for critically reviewing this book chapter. They are also grateful to Ms. Namubiru Halima of The University of Queensland (UQ) for her assistance during the writing of this book chapter.

References

Argent J, Augsburg B, Rasul I (2014) Livestock asset transfers with and without training: evidence from Rwanda. J Econ Behav Organ 108:19-39

Awah Ndukum J, Kudi AC, Bradley G (2010) Prevalence of bovine tuberculosis in abattoirs of the Littoral and Western highland regions of Cameroon: a cause for public health concern. Vet Med Int 2010:495015. https://doi.org/10.4061/2010/495015

Ayele WY, Neill SD, Zinsstag J et al (2004) Bovine tuberculosis: an old disease but a new threat to Africa. Int J Tuberc Lung Dis 8:924-937

Baggett A (2011) Tuberculosis then and now: perspectives on the history of an infectious disease.

Bekele M, Belay I (2011) Evaluation of routine meat inspection procedure to detect bovine tuberculosis suggestive lesions in Jimma Municipal Abattoir, South West Ethiopia. Glob Vet 6:172-179

Bezos J, Casal C, Romero B et al (2014) Current ante-mortem techniques for diagnosis of bovine tuberculosis. Res Vet Sci 97:S44-S52

Biet F, Boschiroli ML, Thorel MF et al (2005) Zoonotic aspects of Mycobacterium bovis and Mycobacterium avium-intracellulare complex (MAC). Vet Res 36:411-436

Biffa D, Bogale A, Skjerve E (2010) Diagnostic efficiency of abattoir meat inspection service in Ethiopia to detect carcasses infected with Mycobacterium bovis: implications for public health. BMC Public Health 10:462

Boukary A, Thys E, Mamadou S et al (2011) La tuberculose a Mycobacterium bovis en Afrique subsaharienne. Ann Med Vet 155:23-37

Bynum H (2011) Tuberculosis then and now: perspectives on the history of an infectious disease. JAMA 305(14):1491-1492

Chadha V (1997) Global trends of tuberculosis - an epidemiological review. NTI Bull 33:11-18

Chatikobo P, Manzi M, Kagarama J et al (2009) Benchmark study on husbandry factors affecting reproductive performance of smallholder dairy cows in the Eastern Province of Rwanda. Livest Res Rural Dev 21(6):83

Cosivi O, Grange J, Daborn C et al (1998) Zoonotic tuberculosis due to Mycobacterium bovis in developing countries. Emerg Infect Dis 4:59

de Valk P (2010) The effect of livestock production on poor and smallholder farmers’ income in Rwanda. Case of ‘one cow one family program’. Dissertation, Institute of Social Studies, The Hague, The Netherlands, p 75

FAO (2007) Composition of meat. http://www.fao.org/ag/againfo/themes/en/meat/backgr_compo sition.html. Accessed 26 Aug 2016

Gafirita J, Umubyeyi AN, Asiimwe BB (2012) A first insight into the genotypic diversity of Mycobacterium tuberculosis from Rwanda. BMC Clin Pathol 12:20

Habarugira G, Rukelibuga J, Nanyingi MO et al (2014) Bovine tuberculosis in Rwanda: prevalence and economic impact evaluation by meat inspection at Societe des Abattoirs de Nyabugogo- Nyabugogo Abattoir, Kigali.

Iredia C, Oguntibeju O, Lewis H et al (2011) Trends and characteristics of patients admitted with musculoskeletal tuberculosis to a referral hospital from 2003 to 2008. Afr J Microbiol Res 5:532-540

Juvenal N, Edward M (2010) Seasonal dynamics and distribution of ticks in Rwanda: implications for tick control strategy in Rwanda. Int J Anim Vet Adv 2:21-25

Kading RC, Borland EM, Cranfield M et al (2013) Prevalence of antibodies to alphaviruses and flaviviruses in free-ranging game animals and nonhuman primates in the greater Congo basin. J Wildl Dis 49:587-599

Karenzi E, Mashaku A, Nshimiyimana AM (2013) Kivuguto traditional fermented milk and the dairy industry in Rwanda. A review. Biotechnol Agron Soc Environ 17(2):383

Katale BZ, Mbugi EV, Kendal S (2012) Bovine tuberculosis at the human-livestock-wildlife interface: is it a public health problem in Tanzania? A review. Onderstepoort J Vet Res 79:84-97

Katigbak MW, Shlasko E, Klein SM (2005) Peritoneal tuberculosis in a 15-month-old male: surgical diagnosis of an insidious disease. Surg Infect 6:255-258

Kazoora HB, Majalija S, Kiwanuka N et al (2014) Prevalence of Mycobacterium bovis skin positivity and associated risk factors in cattle from Western Uganda. Trop Anim Health Prod 46:1383-1390

Kazwala R, Kambarage D, Daborn C et al (2001) Risk factors associated with the occurrence of bovine tuberculosis in cattle in the Southern Highlands of Tanzania. Vet Res Commun 25:609-614

Lorent N, Mugwaneza P, Mugabekazi J et al (2008) Risk factors for delay in the diagnosis and treatment of tuberculosis at a referral hospital in Rwanda. Int J Tuberc Lung Dis 12:392-396

Lorent N, Sebatunzi O, Mukeshimana G et al (2011) Incidence and risk factors of serious adverse events during antituberculous treatment in Rwanda: a prospective cohort study. PLoS One 6(5): e19566

Michel AL, Geoghegan C, Hlokwe T et al (2015) Longevity of Mycobacterium bovis in raw and traditional souring milk as a function of storage temperature and dose.

Nshimiyima J, Nahayo A, Mukamisha P (2013) Prevalence of bovine tuberculosis in Rwanda from 2006 to 2010. Rwanda J Soc Appl Sci 1:43-55

Nzeyimana P, Habarugira G, Udahemuka JC et al (2015) Prevalence of bovine cysticercosis and age relationship at post-mortem in Nyagatare Slaughterhouse. World J Agric Res 3:4-8

Plumptre A (1994) The effects of trampling damage by herbivores on the vegetation of the Pare National des Volcans, Rwanda. AfrJ Ecol 32:115-129

Rawlins R, Pimkina S, Barrett CB et al (2014) Got milk? The impact of Heifer International’s livestock donation programs in Rwanda on nutritional outcomes. Food Policy 44:202-213

Shirima GM, Kazwala RR, Kambarage DM (2003) Prevalence of bovine tuberculosis in cattle in different farming systems in the eastern zone of Tanzania. Prev Vet Med 57:167-172

Shitaye J, Getahun B, Alemayehu T (2006) A prevalence study of bovine tuberculosis by using abattoir meat inspection and tuberculin skin testing data, histopathological and IS6110 PCR examination of tissues with tuberculous lesions in cattle in Ethiopia. Vet Med (Praha) 51 (11):512

Smith RL, Tauer LW, Sanderson MW et al (2014) Minimum cost to control bovine tuberculosis in cow-calf herds. Prev VetMed 115:18-28

Teklu A, Asseged B, Yimer E et al (2004) Tuberculous lesions not detected by routine abattoir inspection: the experience of the Hossana municipal abattoir, southern Ethiopia. Rev Sci Tech 23:957-964

Thoen CO et al (2008) Mycobacterium bovis infection in animals and humans, 2nd edn. Wiley, Hoboken, NJ

Thoen CO, Steele JH, Kaneene JB (2014) Zoonotic tuberculosis: Mycobacterium bovis and other pathogenic mycobacteria, 3rd edn. Wiley-Blackwell, Ames, IA

Trumbo P, Schlicker S, Yates AA et al (2002) Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. J Am Diet Assoc 102:1621-1630

Vordermeier M, Ameni G, Berg S et al (2012) The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia. Comp Immunol Microbiol Infect Dis 35:227-232

Youssef A, Ahmed A (2014) Bovine tuberculosis survey based on meat inspection and microscopic examination in Central City Abattoir in Ismailia, Egypt and its hazards to the abattoir workers. IFRJ 21(2):77-582

Zeru F, Romha G, Berhe G et al (2014) Prevalence of bovine tuberculosis and assessment of cattle owners’ awareness on its public health implication in and around Mekelle, Northern Ethiopia. J Vet Med Anim Health 6:159-167