Associated Neoplasms Kaposi Sarcoma

GENERAL PRINCIPLES

Kaposi sarcoma is caused by coinfection with human herpesvirus-8, also called Kaposi sarcoma- associated herpesvirus.

DIAGNOSIS

In AIDS patients, it commonly presents as cutaneous lesions, but can be disseminated. The GI tract and lungs are the usual visceral organs involved.

TREATMENT

Mild disease is treated with optimization of ART. Severe disease is treated with chemotherapy plus ART. Liposomal doxorubicin is first-line chemotherapy. Cryotherapy or radiation may be useful as well.