CONTENTS
CD8+ T Lymphocytes in HIV-1 Infection.................................................................................... 230
Expansion and Contraction of CD8+ T Lymphocytes during Responses
to Viral Infection...................................................................................................................
230Role of TNF/TNFR Superfamily Members in Homeostasis of CD8+ T Lymphocytes....... 231
Role of Bcl-2 Family Members in CD8+ T Cell Apoptosis.................................................. 231
Role of Common γ-Chain Cytokines in CD8+ T Cell Apoptosis......................................... 231
Role of IFN Type I in CD8+ T Cell Apoptosis...................................................................... 232
Role of Molecules Produced by Effector T Cells in CD8+ T Cell Apoptosis...................... 232
Activation, Proliferation, and Apoptosis of CD8+ T Lymphocytes during HIV Infection.......... 232
Dynamics of CD8+ T Lymphocytes in Chronic HIV-1 Infection......................................... 232
Dynamics of CD8+ T Lymphocytes in Nonpathogenic Chronic HIV-1
and SIV Infection.................................................................................................................... 233
Dynamics of CD8+ T Lymphocytes in Primary HIV-1 Infection......................................... 233
Dysfunction of CD8+ T Cells in HIV-1 Infection................................................................. 234
Increased Rate of CD8+ T Cell Apoptosis in HIV-1 Infection.................................................... 234
Elevated CD8+ T Cell Apoptosis In Vivo............................................................................. 234
Increased Rate of Spontaneous Apoptosis Ex Vivo...............................................................
235Apoptosis in Nonpathogenic HIV-1 and SIV Infections and after HAART.......................... 236
Role of CD95/CD95L Interactions in Elevated Apoptosis of CD8+ T Cells
in HIV-1 Infection.................................................................................................................. 236
Role of TNF/TNFR Interactions and TRAIL in Apoptosis of CD8+
T Lymphocytes in HIV-1 Infection........................................................................................ 237
Role of AICD in Apoptosis of CD8+ T Lymphocytes in HIV-1 Infection........................... 237
Role of HIV-1 Proteins in Elevated Apoptosis of CD8+ T Cells in HIV-1 Infection.......... 237
Other HIV-Related Mechanisms............................................................................................ 238
Summary........................................................................................................................................ 238
Acknowledgments......................................................................................................................... 238
References..................................................................................................................................... 239
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