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Appendix Ear Product Formulary

This formulary is presented as a guide to products available for treating ear disease. The products listed are for topical use in the ear canal unless indicated otherwise.

Many topical formulations are compounded mixtures containing ingredi­ents that may be potentially ototoxic when there is no eardrum. Consult the manu­facturer for the recommendation for use when the eardrum is perforated.

The organization of the formulary is by function or mode of action. Ingredients are categorized as antiinflammatory, antibacterial, antifungal, miticidal, ear cleaners, and drying agents. Some formulations have more than one function and may be listed again in the appropriate sections. Under each category, the generic ingredient, the trade name, and the manufacturers are listed. The proprietary names and active ingredients of products are listed after the ingredients.

Active Ingredients of Ear Products, Listed by Function

POTENT ANTIINFLAMMATORY AGENTS

Betamethasone 0.1% Genta-Otic Vetus
Gentaved Otic Vedco
Gentocin Otic Schering-Plough
Otomax Schering-Plough
Tri-Otic Med-Pharmex
Betamethasone 0.64 mg Lotrisone Schering-Plough
Dexamethasone 0.1%c Decadron Phosphate Merck
Tobradex Alcon
Tresaderm Merial
Fluocinolone 0.01%c Synotic Otic Ft. Dodge

MODERATE ANTIINFLAMMATORY AGENTS

Isoflupredone acetate 0.1% Neo-Predef Upjohn and Pharmacia
Tritop Upjohn and Pharmacia
Triamcinolone acetonide 0.1% Animax Pharmaderm
Coly-Mycin S Otic Parke-Davis
Cortisporin Otic Glaxo Wellcome
Derma 4 Ointment Pfizer
Dermalone Vedco
Derma-Vet Med-Pharmex
Forte Topical Upjohn and Pharmacia
Neo-Predef Upjohn and Pharmacia
Panolog Solvay
MILD ANTIINFLAMMATORY AGENTS
Hydrocortisone acetate 0.2%c Forte Topical Upjohn and Pharmacia
Hydrocortisone 1% Bur-O-Cort Q.A.
Labs
Burotic HC Allerderm
Cipro HC Otic Bayer Pharmaceutical
Clear X Ear DVM
Drying Solution

Active Ingredients of Ear Products, Listed by Function—cont'd

Prednisolone 0.17% Coly-Mycin S Otic CORT/ASTRIN Cortisporin Otic Epiotic HC VoSol HC Otic Chlora-Otic Liquichlor Parke-Davis

Vedco

Glaxo Wellcome

Allerderm

Wallace

Vetus

Evsco

ANTIBACTERIALS
Acetic acid-boric acid DermaPet Ear/Skin DermaPet, Inc.
Cleanser
Chloramphenicol Chlora-Otic Vetus
Chloromycetin Otic Parke-Davis
Liquichlor Evsco
Ciprofloxacin Cipro HC Otic Bayer Pharmaceuticals
Colistin Coly-Mycin S Otic Parke-Davis
Enrofloxacin Baytril Injection Bayer Pharmaceuticals

(Mix 2 ml in 13 ml of artificial tears or saline)

Gentamicin Genta-Otic Vetus
Gentaved Otic Vedco
Gentocin Otic Schering-Plough
Otomax Schering-Plough
Topagen Ointment Schering-Plough
Tri-Otic Med-Pharmex
Neomycin Animax Pharmaderm
Coly-Mycin S Otic Parke-Davis
Cortisporin Otic Glaxo Wellcome
Derma 4 Ointment Pfizer
Dermalone Vedco
Derma-Vet Med-Pharmex
Forte Topical Upjohn and

Pharmacia

Neo-Predef Upjohn and

Pharmacia

Panolog Solvay
Quadritop Vetus
Tresaderm Merial
Tritop Upjohn and Pharmacia
Ofloxacin Floxin Otic Daiichi
Polymyxin B sulfate Cortisporin Glaxo Wellcome
Forte Topical Upjohn and Pharmacia
Silver sulfadiazine 0.1% Silvadene Creme Marion

(Mix 1.5 ml of cream in 13.5 ml of distilled water)

Ticarcillin

Ticar 1 g vial SmithKline Beecham

Active Ingredients of Ear Products, Listed by Function—cont'd

(Mix with 2 ml of sterile water. Add 0.5 ml of this solution to 15 ml of artificial tears or saline.
Keep refrigerated. Use as ear drops for 1 week, then discard remaining solution.)

Freeze the remainder in 0.5-ml increments for future use; good for 90 days frozen.

Tobramycin Tobradex Ophthalmic Alcon
Tris-EDTA TrizEDTA DermaPet, Inc.
T8 Solution Ear Rinse DVM
ANTIFUNGALS
Acetic acid-boric acid DermaPet Ear/Skin

Cleanser

DermaPet, Inc.
Clotrimazole 1% Lotrimin AF Schering-Plough
Lortisone Schering-Plough
Otomax Schering-Plough
Tri-Otic Med-Pharmex
Miconazole 1% Conofite Mallinckrodt
Micazole Vetus
Miconosol Med-Pharmex
Nystatin 100,000 U/ml Animax Pharmaderm
Derma-4 Pfizer
Dermalone Vedco
Derma-Vet Med-Pharmex
Panolog Solvay
Quadritop Vetus
Zinc undecylenate Fungi-dry-ear Q.A. Labs
Miticidals
Fipronil Frontline Top Spot Merial
Ivermectin 1% injectable Ivomec 1% Merial

(0.1 ml/10 lb subcutaneously every 2 weeks for three injections)

Pyrethrins Aurimite Schering-Plough
Cerumite Evsco
Eradimite Solvay
Mita-Clear Pfizer
Nolvamite with Ft. Dodge
Nolvasan
Oticare-M Ear Mite ARC
Treatment
Otomite Plus Allerderm
Rotenone 0.12% Mitaplex-R Tomlyn
Rotenone 0.12% and Ear Mite Lotion DurVet
cube resins 0.16%
Ear Miticide Vedco
Ear Miticide Phoenix
Thiabendazole Tresaderm Merial

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Source: Gotthelf Louis N.. Small Animal Ear Diseases: An Illustrated Guide. 2nd ed. — Saunders,2004. — 384 p.. 2004
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