CONTENTS
Introduction....................................................................................................................................... 3
Lentiviral Biology and Pathogenesis................................................................................................
3The Origins of HIV-1 and the Emergence of Lentiviral Disease in Primates.......................... 5
Replication and Pathogenesis: A Comparative Lentiviral Perspective.................................... 5
Viral Life Cycle................................................................................................................................. 6
Early Events............................................................................................................................... 6
Uncoating and Transport to the Nucleus................................................................................... 8
Integration.................................................................................................................................. 8
Latency....................................................................................................................................... 9
Late Events............................................................................................................................... 10
Conclusion....................................................................................................................................... 11
Acknowledgment............................................................................................................................. 11
References....................................................................................................................................... 11
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