Coronary Artery Lesions
It was a surprise for us to discover, during post-mortem examination, many severe latent coronary artery lesions occurring in very young (23-31 years old) AIDS patients [1]. Both hospital and forensic necropsies were performed.
The death causes were not linked with coronary lesions except in one of five sudden death cases without other pathology. Clinical coronary disease symptoms were absent in all patients. The patients were homosexuals or drug addicts or both. Pathological analysis used transverse sections taken every 0.5 cm along the epicardial routes of the three main coronary trunks. Sections obtained every 1 cm were fixed in Bouin’s solution, then embedded in paraffin for histopathological study, together with representative fragments of the left and right ventricular walls and interventricular septum making up the distal coronary network. Histological sections were stained with hemalum-phloxine-saffron and with Weigert’s resorcin-fuchsin method. Every coronary examination of AIDS patients pointed out gross and microscopic lesions (100 %), although a comparative examination of patients of the same age without AIDS showed only 14% of identical lesions.
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