Vagina
Malignant tumours of the vagina
Primary malignant tumours of the vagina are uncommon, constituting about 2% of all genital tract tumours. Most (80%) vaginal malignancies represent metastatic spread.
Tumours confined to the vagina are usually treated by radical hysterectomy and vaginectomy. Squamous cell carcinomas account for over 90% of primary vaginal malignancies. Prognosis is related to the extent of spread of the tumour at the time of its discovery. The 5-year survival rate for tumours confined to the vagina (stage I) is 80%, whereas it is only 20% for those with extensive spread (stages III/IV) (1).Embryonal rhabdomyosarcoma (sarcoma botryoides)
Embryonal rhabdomyosarcoma occurs almost exclusively in girls under 4 years old. It arises in the lamina propria of the vagina and consists of primitive spindle rhabdomyoblasts, some of which show cross-striations. Tumours less than 3 cm in greatest dimension tend to be localized and may be cured by wide excision and chemotherapy. Larger tumours have often spread to adjacent structures, regional lymph nodes, or distant sites. Even in advanced cases, half of patients survive with radical surgery and chemotherapy (1, 2).
More on the topic Vagina:
- Sample collection
- Introduction
- ANORECTAL MALFORMATIONS
- Cases
- References
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- Ovary and reproductive tract
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- Male reproductive system
- Clinical evaluation of pelvic organ prolapse