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Other cells

Monocytic cells comprise a very low percentage of nucleated cells in marrow. The earliest recognizable form is the monoblast, which has an oval to slightly indented nucleus surrounded by a scant amount of dark blue cytoplasm.

The N:C of monoblasts is generally lower than that of myeloblasts. Promonocytes have indented to irregular-shaped nuclei, gray-blue cytoplasm devoid of granules, and possibly a few cytoplasmic small vacuoles. Monocytes in marrow aspirates have horseshoe- or butterfly-shaped nuclei and light gray-blue cytoplasm that may contain a few small vacuoles, similar to monocytes in blood.

Plasma cells and small lymphocytes are morphologically similar as in other tissues and comprise a small percentage of cells in the marrow of dogs (Table 19.1). In healthy young cats, lymphocytes can make up ~15–20% of marrow nucleated cells, but this proportion decreases with progressive age. Macrophages containing metarubricyte nuclei and hemosiderin are regularly observed in marrow films, and rare individual mast cells may also be present.

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Source: Barger A.M., MacNeill A.L. (Eds.). Small Animal Cytologic Diagnosis: Canine and Feline Disease. CRC Press,2024. — 536 p.. 2024
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